Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection

Recent successes with monoclonal antibody cocktails ZMapp(TM) and MIL77 against Ebola virus (EBOV) infections have reignited interest in antibody-based therapeutics. Since the production process for monoclonal antibodies can be prolonged and costly, alternative treatments should be investigated. We...

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Publicado no:Sci Rep
Main Authors: Zheng, Xuexing, Wong, Gary, Zhao, Yongkun, Wang, Hualei, He, Shihua, Bi, Yuhai, Chen, Weijin, Jin, Hongli, Gai, Weiwei, Chu, Di, Cao, Zengguo, Wang, Chong, Fan, Quanshui, Chi, Hang, Gao, Yuwei, Wang, Tiecheng, Feng, Na, Yan, Feihu, Huang, Geng, Zheng, Ying, Li, Nan, Li, Yuetao, Qian, Jun, Zou, Yong, Kobinger, Gary, Gao, George Fu, Qiu, Xiangguo, Yang, Songtao, Xia, Xianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828711/
https://ncbi.nlm.nih.gov/pubmed/27067649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24179
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