Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model

Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV, prophylactic and therapeutic treatments are urgently needed. In this study, we prepared purified equine F(ab’)(2) from horses immunized with...

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Pubblicato in:Antiviral Res
Autori principali: Zhao, Yongkun, Wang, Chong, Qiu, Boning, Li, Chufang, Wang, Hualei, Jin, Hongli, Gai, Weiwei, Zheng, Xuexing, Wang, Tiecheng, Sun, Weiyang, Yan, Feihu, Gao, Yuwei, Wang, Qian, Yan, Jinghua, Chen, Ling, Perlman, Stanley, Zhong, Nanshan, Zhao, Jincun, Yang, Songtao, Xia, Xianzhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Published by Elsevier B.V. 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113855/
https://ncbi.nlm.nih.gov/pubmed/27890674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.11.016
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