Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions

CD4 and CD8 T lymphocyte activation requires the generation of sufficient energy to support new biosynthetic demands. Following T cell receptor (TCR) engagement, these requirements are met by an increased glycolysis, due, at least in part, to induction of the Glut1 glucose transporter. As Glut1 is u...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Cretenet, Gaspard, Clerc, Isabelle, Matias, Maria, Loisel, Severine, Craveiro, Marco, Oburoglu, Leal, Kinet, Sandrina, Mongellaz, Cédric, Dardalhon, Valérie, Taylor, Naomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828702/
https://ncbi.nlm.nih.gov/pubmed/27067254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24129
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky