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The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a non-healing strain of Leishmania major in C57BL/6 mice

Infection of C57BL/6 mice with most L. major strains results in a healing lesion and clearance of parasites from the skin. Infection of C57BL/6 mice with the L. major Seidman strain (LmSd) isolated from a patient with chronic lesions, despite eliciting a strong Th1 response, results in a non-healing...

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Detalles Bibliográficos
Publicado en:Eur J Immunol
Main Authors: Charmoy, Melanie, Hurrell, Benjamin P., Romano, Audrey, Lee, Sang Hun, Ribeiro-Gomes, Flavia, Riteau, Nicolas, Mayer-Barber, Katrin, Tacchini-Cottier, Fabienne, Sacks, David L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828310/
https://ncbi.nlm.nih.gov/pubmed/26689285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546015
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