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The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a non-healing strain of Leishmania major in C57BL/6 mice
Infection of C57BL/6 mice with most L. major strains results in a healing lesion and clearance of parasites from the skin. Infection of C57BL/6 mice with the L. major Seidman strain (LmSd) isolated from a patient with chronic lesions, despite eliciting a strong Th1 response, results in a non-healing...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828310/ https://ncbi.nlm.nih.gov/pubmed/26689285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546015 |
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