IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL/6 Mice

Experimental infection with the protozoan parasite Leishmania major has been extensively used to understand the mechanisms involved in T helper cell differentiation. Following infection, C57BL/6 mice develop a small self-healing cutaneous lesion and they are able to control parasite burden, a proces...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Descatoire, Marc, Hurrell, Benjamin P., Govender, Melissa, Passelli, Katiuska, Martinez-Salazar, Berenice, Hurdayal, Ramona, Brombacher, Frank, Guler, Reto, Tacchini-Cottier, Fabienne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641309/
https://ncbi.nlm.nih.gov/pubmed/29067025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01265
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