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Combining Single-molecule Manipulation and Imaging for the Study of Protein-DNA Interactions
The paper describes the combination of optical tweezers and single molecule fluorescence detection for the study of protein-DNA interaction. The method offers the opportunity of investigating interactions occurring in solution (thus avoiding problems due to closeby surfaces as in other single molecu...
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| Pubblicato in: | J Vis Exp |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MyJove Corporation
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828021/ https://ncbi.nlm.nih.gov/pubmed/25226304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51446 |
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