Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

[Image: see text] The formation of reactive oxygen species (ROS) is linked to the pathogenesis of neurodegenerative diseases. Here we have investigated the effect of soluble and aggregated amyloid-β (Aβ) and α-synuclein (αS), associated with Alzheimer’s and Parkinson’s diseases, respectively, on the...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Pedersen, Jeppe T., Chen, Serene W., Borg, Christian B., Ness, Samuel, Bahl, Justyna M., Heegaard, Niels H. H., Dobson, Christopher M., Hemmingsen, Lars, Cremades, Nunilo, Teilum, Kaare
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827876/
https://ncbi.nlm.nih.gov/pubmed/26967463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13577
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