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Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

The small GTPase Rab5 has been well defined to control the vesicle-mediated plasma membrane protein transport to the endosomal compartment. However, its function in the internalization of vascular endothelial (VE)-cadherin, an important component of adherens junctions, and as a result regulating the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Life Sci
Hauptverfasser: Yang, Junjun, Yao, Wei, Qian, Guisheng, Wei, Zhenghua, Wu, Guangyu, Wang, Guansong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827161/
https://ncbi.nlm.nih.gov/pubmed/26112597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1973-4
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