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Regulation of β-Adrenergic Receptor Trafficking and Lung Microvascular Endothelial Cell Permeability by Rab5 GTPase

Rab5 GTPase modulates the trafficking of the cell surface receptors, including G protein-coupled β-adrenergic receptors (β-ARs). Here, we have determined the role of Rab5 in regulating the internalization of β-ARs in lung microvascular endothelial cells (LMECs) and in maintaining the integrity and p...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Yang, Junjun, Sun, Huan, Zhang, Jihang, Hu, Mingdong, Wang, Jianchun, Wu, Guangyu, Wang, Guansong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495405/
https://ncbi.nlm.nih.gov/pubmed/26157342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12045
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