MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints

BACKGROUND: Antibody therapeutic targeting of the immune checkpoints cytotoxic T-lymphocyte-associated molecule 4 (CTLA-4) and programmed cell death 1 (PD-1) has demonstrated marked tumor regression in clinical trials. MicroRNAs (miRNAs) can modulate multiple gene transcripts including possibly more...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Wei, Jun, Nduom, Edjah K., Kong, Ling-Yuan, Hashimoto, Yuuri, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Fuller, Greg N., Gilbert, Mark R., Overwijk, Willem, Calin, George A., Heimberger, Amy B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827047/
https://ncbi.nlm.nih.gov/pubmed/26658052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov292
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