O6.01 TARGETING THE IMMUNE CHECKPOINT NETWORK WITH MIR-138 EXERTS THERAPEUTIC EFFICACY IN MURINE MODELS OF GLIOMA

Antibody therapeutic targeting of the immune checkpoints CTLA-4 and PD-1 has demonstrated marked tumor regression in clinical trials; however, this requires multimodality treatment and has known toxicity. Furthermore, the targeting of one checkpoint often results in the up-regulation of another. Mic...

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Detalhes bibliográficos
Main Authors: Heimberger, A., Wei, J., Nduom, E., Kong, L., Ivan, C., Fuller, G.N., Gilbert, M.R., Conrad, C.A., Calin, G.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Oral Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185794/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.42
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