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O6.01 TARGETING THE IMMUNE CHECKPOINT NETWORK WITH MIR-138 EXERTS THERAPEUTIC EFFICACY IN MURINE MODELS OF GLIOMA
Antibody therapeutic targeting of the immune checkpoints CTLA-4 and PD-1 has demonstrated marked tumor regression in clinical trials; however, this requires multimodality treatment and has known toxicity. Furthermore, the targeting of one checkpoint often results in the up-regulation of another. Mic...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185794/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.42 |
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