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Treg depletion in non‐human primates using a novel diphtheria toxin‐based anti‐human CCR4 immunotoxin
Regulatory T cells (Treg) play an important role in modulating the immune response and has attracted increasing attention in diverse fields such as cancer treatment, transplantation and autoimmune diseases. CC chemokine receptor 4 (CCR4) is expressed on the majority of Tregs, especially on effector...
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Publicado en: | Mol Oncol |
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Autores principales: | , , , , , , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826841/ https://ncbi.nlm.nih.gov/pubmed/26643572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.11.008 |
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