Treg depletion in non‐human primates using a novel diphtheria toxin‐based anti‐human CCR4 immunotoxin

Regulatory T cells (Treg) play an important role in modulating the immune response and has attracted increasing attention in diverse fields such as cancer treatment, transplantation and autoimmune diseases. CC chemokine receptor 4 (CCR4) is expressed on the majority of Tregs, especially on effector...

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Vydáno v:Mol Oncol
Hlavní autoři: Wang, Zhaohui, Pratts, Shannon G., Zhang, Huiping, Spencer, Philip J., Yu, Ruichao, Tonsho, Makoto, Shah, Jigesh A., Tanabe, Tatsu, Powell, Harrison R., Huang, Christene A., Madsen, Joren C., Sachs, David H., Wang, Zhirui
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826841/
https://ncbi.nlm.nih.gov/pubmed/26643572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.11.008
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