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Aldose Reductase acts as a Selective Derepressor of PPARγ and Retinoic Acid Receptor
Histone deacetylase 3 (HDAC3), a chromatin modifying enzyme, requires association with the deacetylase containing domain (DAD) of the nuclear receptor co-repressors NCOR1 and SMRT for its stability and activity. Here we show that aldose reductase (AR), the rate-limiting enzyme of the polyol pathway,...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826833/ https://ncbi.nlm.nih.gov/pubmed/27052179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.086 |
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