Novel Role for Aldose Reductase in Mediating Acute Inflammatory Responses in the Lung()

Exaggerated inflammatory responses and the resultant increases in alveolar-capillary permeability underlie the pathogenesis of acute lung injury during sepsis. This study examined the functions of aldose reductase (AR) in mediating acute lung inflammation. Transgenic mice expressing human AR (ARTg)...

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Bibliographic Details
Main Authors: Ravindranath, Thyyar M., Mong, Phyllus Y., Ananthakrishnan, Radha, Li, Qing, Quadri, Nosirudeen, Schmidt, Ann Marie, Ramasamy, Ravichandran, Wang, Qin
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144631/
https://ncbi.nlm.nih.gov/pubmed/20007578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900720
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