Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

Oxidative stress and enhanced lipid peroxidation are linked to many chronic inflammatory diseases, including age-related macular degeneration (AMD). AMD is the leading cause of blindness in Western societies, but its aetiology remains largely unknown. Malondialdehyde (MDA) is a common lipid peroxida...

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Publicado en:Nature
Autores principales: Weismann, David, Hartvigsen, Karsten, Lauer, Nadine, Bennett, Keiryn L., Scholl, Hendrik P. N., Issa, Peter Charbel, Cano, Marisol, Brandstätter, Hubert, Tsimikas, Sotirios, Skerka, Christine, Superti-Furga, Giulio, Handa, James T., Zipfel, Peter F., Witztum, Joseph L., Binder, Christoph J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826616/
https://ncbi.nlm.nih.gov/pubmed/21979047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10449
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