The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay

Gene duplication is a major evolutionary force driving adaptation and speciation, as it allows for the acquisition of new functions and can augment or diversify existing functions. Here, we report a gene duplication event that yielded another outcome – the generation of antagonistic functions. One p...

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Pubblicato in:Cell
Autori principali: Shum, Eleen Y., Jones, Samantha H., Shao, Ada, Chousal, Jennifer N., Krause, Matthew D., Chan, Wai-Kin, Lou, Chih-Hong, Espinoza, Josh L., Song, Hye-Won, Phan, Mimi H., Ramaiah, Madhuvanthi, Huang, Lulu, McCarrey, John R., Peterson, Kevin J., De Rooij, Dirk G., Cook-Andersen, Heidi, Wilkinson, Miles F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826573/
https://ncbi.nlm.nih.gov/pubmed/27040500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.046
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