A computational method for designing diverse linear epitopes including citrullinated peptides with desired binding affinities to intravenous immunoglobulin

BACKGROUND: Understanding the interactions between antibodies and the linear epitopes that they recognize is an important task in the study of immunological diseases. We present a novel computational method for the design of linear epitopes of specified binding affinity to Intravenous Immunoglobulin...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Patro, Rob, Norel, Raquel, Prill, Robert J., Saez-Rodriguez, Julio, Lorenz, Peter, Steinbeck, Felix, Ziems, Bjoern, Luštrek, Mitja, Barbarini, Nicola, Tiengo, Alessandra, Bellazzi, Riccardo, Thiesen, Hans-Jürgen, Stolovitzky, Gustavo, Kingsford, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826543/
https://ncbi.nlm.nih.gov/pubmed/27059896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1008-7
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