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Slowing of Contractile Kinetics by Myosin-Binding Protein C Can Be Explained by Its Cooperative Binding to the Thin Filament

Cardiac myosin binding protein C (cMyBP-C) is a thick filament-associated protein that participates in the regulation of muscle contraction. Simplified in vitro systems show that cMyBP-C binds not only to myosin, but also to the actin filament. The physiological significance of these separate bindin...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Wang, Clinton, Schwan, Jonas, Campbell, Stuart G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826328/
https://ncbi.nlm.nih.gov/pubmed/26454159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.007
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