Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop

Obesity has long been linked with prostate cancer progression, although the underlying mechanism is still largely unknown. Here, we report that adipocytes promote the enrichment of prostate cancer stem cells (CSCs) through a vicious cycle of autocrine amplification. In the presence of adipocytes, pr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Tang, Kai-Dun, Liu, Ji, Jovanovic, Lidija, An, Jiyuan, Hill, Michelle M., Vela, Ian, Lee, Terence Kin-Wah, Ma, Stephanie, Nelson, Colleen, Russell, Pamela J., Clements, Judith A., Ling, Ming-Tat
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2015
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826255/
https://ncbi.nlm.nih.gov/pubmed/26700819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6643
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