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Autocrine amplification loop in statin-induced apoptosis of human melanoma cells

BACKGROUND AND PURPOSE: Beside their cholesterol lowering effect, statins exert pleiotropic effects, which include anti-inflammatory, immunosuppressive and anti-proliferative actions. In higher concentrations, statins trigger apoptosis in primary cells and tumour cells. In particular, melanoma cells...

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Detalhes bibliográficos
Main Authors: Minichsdorfer, C, Hohenegger, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743847/
https://ncbi.nlm.nih.gov/pubmed/19563533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00298.x
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