Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy

Pancreatic cancer is one of the most lethal tumor types worldwide and an effective therapy is still elusive. Targeted therapy focused against a specific alteration is by definition unable to attack broad pathway signaling modification. Tumor heterogeneity will render targeted therapies ineffective b...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Werner, Kristin, Lademann, Franziska, Thepkaysone, May-Linn, Jahnke, Beatrix, Aust, Daniela E., Kahlert, Christoph, Weber, Georg, Weitz, Jürgen, Grützmann, Robert, Pilarsky, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826184/
https://ncbi.nlm.nih.gov/pubmed/26716649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6766
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