Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis

BACKGROUND: Pancreatic ductal adenocarcinoma shows a distinct apoptosis resistance, which contributes significantly to the aggressive nature of this tumor and constrains the effectiveness of new therapeutic strategies. Apoptosis resistance is determined by the net balance of the cells pro-and anti-a...

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Detaylı Bibliyografya
Asıl Yazarlar: Rückert, Felix, Samm, Nicole, Lehner, Anne-Kathrin, Saeger, Hans-Detlev, Grützmann, Robert, Pilarsky, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912871/
https://ncbi.nlm.nih.gov/pubmed/20646298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-379
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