Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis

Podoplanin/Aggrus is a sialoglycoprotein expressed in various cancers. We previously identified podoplanin as a key factor in tumor-induced platelet aggregation. Podoplanin-mediated platelet aggregation enhances tumor growth and metastasis by secreting growth factors and by forming tumor emboli in t...

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Vydáno v:Oncotarget
Hlavní autoři: Sekiguchi, Takaya, Takemoto, Ai, Takagi, Satoshi, Takatori, Kazuki, Sato, Shigeo, Takami, Miho, Fujita, Naoya
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826181/
https://ncbi.nlm.nih.gov/pubmed/26684030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6598
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