Suppression of Aggrus/podoplanin-induced platelet aggregation and pulmonary metastasis by a single-chain antibody variable region fragment

Almost all highly metastatic tumor cells possess high platelet aggregating abilities, thereby form large tumor cell-platelet aggregates in the microvasculature. Embolization of tumor cells in the microvasculature is considered to be the first step in metastasis to distant organs. We previously ident...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Miyata, Kenichi, Takagi, Satoshi, Sato, Shigeo, Morioka, Hiroshi, Shiba, Kiyotaka, Minamisawa, Tamiko, Takami, Miho, Fujita, Naoya
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298386/
https://ncbi.nlm.nih.gov/pubmed/25132683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.320
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