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Interacting domains in the epithelial sodium channel that mediate proteolytic activation

Epithelial Sodium Channel (ENaC) proteolysis at sites in the extracellular loop of the α and γ subunits leads to marked activation. The mechanism of this effect remains debated, as well as the role of the N- and C-terminal fragments of these subunits created by cleavage. We introduced cysteines at s...

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Библиографические подробности
Опубликовано в: :Channels (Austin)
Главные авторы: Berman, Jonathan M, Awayda, Ryan G, Awayda, Mouhamed S
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826093/
https://ncbi.nlm.nih.gov/pubmed/26218672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1073869
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