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Effects of urine composition on epithelial Na(+) channel-targeted protease activity

We examined human urinary proteolytic activity toward the Epithelial Sodium Channel (ENaC). We focused on two sites in each of alpha and gamma ENaC that are targets of endogenous and exogenous proteases. We examined the effects of ionic strength, pH and urinary H(+)-buffers, metabolic intermediates,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Rep
Hauptverfasser: Berman, Jonathan M, Awayda, Ryan G, Awayda, Mouhamed S
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673640/
https://ncbi.nlm.nih.gov/pubmed/26564065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12611
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