Identification of Low- and High-Impact Hemagglutinin Amino Acid Substitutions That Drive Antigenic Drift of Influenza A(H1N1) Viruses

Determining phenotype from genetic data is a fundamental challenge. Identification of emerging antigenic variants among circulating influenza viruses is critical to the vaccine virus selection process, with vaccine effectiveness maximized when constituents are antigenically similar to circulating vi...

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Udgivet i:PLoS Pathog
Main Authors: Harvey, William T., Benton, Donald J., Gregory, Victoria, Hall, James P. J., Daniels, Rodney S., Bedford, Trevor, Haydon, Daniel T., Hay, Alan J., McCauley, John W., Reeve, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825936/
https://ncbi.nlm.nih.gov/pubmed/27057693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005526
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