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Long term Glycemic Control Using Polymer Encapsulated, Human Stem-Cell Derived β-cells in Immune Competent mice

The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in diabetic patients(1). Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically(2), but are limited by the adverse effects of lifetime im...

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Publicat a:Nat Med
Autors principals: Vegas, Arturo J., Veiseh, Omid, Gürtler, Mads, Millman, Jeffrey R., Pagliuca, Felicia W., Bader, Andrew R., Doloff, Joshua C., Li, Jie, Chen, Michael, Olejnik, Karsten, Tam, Hok Hei, Jhunjhunwala, Siddharth, Langan, Erin, Aresta-Dasilva, Stephanie, Gandham, Srujan, McGarrigle, James, Bochenek, Matthew A., Hollister-Lock, Jennifer, Oberholzer, Jose, Greiner, Dale L., Weir, Gordon C., Melton, Douglas A., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825868/
https://ncbi.nlm.nih.gov/pubmed/26808346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4030
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