Long term Glycemic Control Using Polymer Encapsulated, Human Stem-Cell Derived β-cells in Immune Competent mice

The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in diabetic patients(1). Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically(2), but are limited by the adverse effects of lifetime im...

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Publicado no:Nat Med
Main Authors: Vegas, Arturo J., Veiseh, Omid, Gürtler, Mads, Millman, Jeffrey R., Pagliuca, Felicia W., Bader, Andrew R., Doloff, Joshua C., Li, Jie, Chen, Michael, Olejnik, Karsten, Tam, Hok Hei, Jhunjhunwala, Siddharth, Langan, Erin, Aresta-Dasilva, Stephanie, Gandham, Srujan, McGarrigle, James, Bochenek, Matthew A., Hollister-Lock, Jennifer, Oberholzer, Jose, Greiner, Dale L., Weir, Gordon C., Melton, Douglas A., Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825868/
https://ncbi.nlm.nih.gov/pubmed/26808346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4030
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