Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance

Cisplatin (cis-diaminedichloroplatin (II), CDDP) is part of the standard therapy for a number of solid tumors including Non-Small-Cell Lung Cancer (NSCLC). The initial response observed is in most cases only transient and tumors quickly become refractory to the drug. Tumor cell resistance to CDDP re...

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Publicado no:Cell Cycle
Main Authors: Sourisseau, Tony, Helissey, Carole, Lefebvre, Céline, Ponsonnailles, Florence, Malka-Mahieu, Hélène, Olaussen, Ken A, André, Fabrice, Vagner, Stephan, Soria, Jean-Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825832/
https://ncbi.nlm.nih.gov/pubmed/26825230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1120918
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