TopBP1-mediated DNA processing during mitosis

Maintenance of genome integrity is crucial to avoid cancer and other genetic diseases. Thus faced with DNA damage, cells mount a DNA damage response to avoid genome instability. The DNA damage response is partially inhibited during mitosis presumably to avoid erroneous processing of the segregating...

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Udgivet i:Cell Cycle
Main Authors: Gallina, Irene, Christiansen, Signe Korbo, Pedersen, Rune Troelsgaard, Lisby, Michael, Oestergaard, Vibe H.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825820/
https://ncbi.nlm.nih.gov/pubmed/26701150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1128595
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