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PTH-IGF SIGNALING PROMOTES BONE FORMATION THROUGH GLYCOLYSIS: PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

Teriparatide, a recombinant peptide corresponding to amino acids 1-34 of human parathyroid hormone (PTH), has been an effective bone anabolic drug for over a decade. However, the mechanism whereby PTH stimulates bone formation remains poorly understood. Here we report that in cultures of osteoblast-...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Bone Miner Res
Egile Nagusiak: Esen, Emel, Lee, Seung-Yon, Wice, Burton M, Long, Fanxin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825329/
https://ncbi.nlm.nih.gov/pubmed/25990470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2556
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