Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B(12) supplementation

The objectives of this single-center, open-label, phase II study were to evaluate (a) the feasibility and safety of neoadjuvant administration of pemetrexed with oral folic acid and vitamin B(12) (FA/B(12)) in newly diagnosed patients with resectable rectal cancer and (b) intracellular and systemic...

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Detalhes bibliográficos
Publicado no:Anticancer Drugs
Main Authors: Stoffregen, Clemens C., Odin, Elisabeth A., Carlsson, Göran U., Kurlberg, Göran K., Björkqvist, Hillevi G., Tångefjord, Maria T., Gustavsson, Bengt G.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Clinical Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825111/
https://ncbi.nlm.nih.gov/pubmed/26825869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000345
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