A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma

Herein, we have identified cross-talk between the Hippo and fibroblast growth factor receptor (FGFR) oncogenic signaling pathways in cholangiocarcinoma (CCA). Yes-associated protein (YAP) nuclear localization and up-regulation of canonical target genes was observed in CCA cell lines and a patient-de...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ilyas, Sumera I., Yamada, Daisaku, Hirsova, Petra, Bronk, Steven F., Werneburg, Nathan W., Krishnan, Anuradha, Salim, Warda, Zhang, Liang, Trushina, Eugenia, Truty, Mark J., Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825008/
https://ncbi.nlm.nih.gov/pubmed/26826125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698472
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