YAP-associated chromosomal instability and cholangiocarcinoma in mice

Deregulated Hippo pathway signaling is associated with aberrant activation of the downstream effector yes-associated protein (YAP), an emerging key oncogenic mediator in cholangiocarcinoma (CCA). In our prior work, we have demonstrated that biliary transduction of YAP along with Akt as a permissive...

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Udgivet i:Oncotarget
Main Authors: Ilyas, Sumera, Fischbach, Samantha R., Bronk, Steven F., Hirsova, Petra, Krishnan, Anuradha, Dhanasekaran, Renumathy, Smadbeck, James B., Smoot, Rory L., Vasmatzis, George, Gores, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814182/
https://ncbi.nlm.nih.gov/pubmed/29464042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23638
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