Loading...
A Simple Method for Enhancing the Bioorthogonality of Cyclooctyne Reagent
The cross-reactivity between some cyclooctynes and thiols limits the bioorthogonality of the strain-promoted azide–alkyne cycloaddition reaction. We show that a low concentration of β-mercaptoethanol significantly reduces the undesirable side reaction between bicyclononyne (BCN) and cysteine and whi...
Na minha lista:
| Udgivet i: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824645/ https://ncbi.nlm.nih.gov/pubmed/27009873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc01321j |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|