A carregar...

A Simple Method for Enhancing the Bioorthogonality of Cyclooctyne Reagent

The cross-reactivity between some cyclooctynes and thiols limits the bioorthogonality of the strain-promoted azide–alkyne cycloaddition reaction. We show that a low concentration of β-mercaptoethanol significantly reduces the undesirable side reaction between bicyclononyne (BCN) and cysteine and whi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Tian, He, Sakmar, Thomas P., Huber, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824645/
https://ncbi.nlm.nih.gov/pubmed/27009873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc01321j
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!