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ITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to ally

ITPRs (inositol 1,4,5-trisphosphate receptors), the main endoplasmic reticulum (ER) Ca(2+)-release channels, were originally proposed as suppressors of autophagy. Yet, new evidence has accumulated over recent years supporting a crucial, stimulatory role for ITPRs in driving the autophagic flux. Here...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Decuypere, Jean-Paul, Parys, Jan B, Bultynck, Geert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824608/
https://ncbi.nlm.nih.gov/pubmed/26291777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1083666
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