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The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca(2+)-release channel

The inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) type 2 (IP(3)R2) is an intracellular Ca(2+)-release channel located on the endoplasmic reticulum (ER). It displays in many cell types a predominantly perinuclear or even nuclear localization. IP(3)R2 is characterized by a high sensitivity to...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: VERVLOESSEM, Tamara, YULE, David I., BULTYNCK, Geert, PARYS, Jan B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465056/
https://ncbi.nlm.nih.gov/pubmed/25499268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.12.006
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