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Frameshift mutation of UVRAG: Switching a tumor suppressor to an oncogene in colorectal cancer
Colorectal cancer (CRC) ranks as the second leading cause of cancer-related deaths in the Western world. It has a nearly 50% metastasis rate and only a subset of patients respond to current treatment strategy. UVRAG, a key autophagy effector and a guardian of chromosomal stability, is truncated by a...
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| Pubblicato in: | Autophagy |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824576/ https://ncbi.nlm.nih.gov/pubmed/26327192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1086523 |
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