GABARAP-mediated targeting of PI4K2A/PI4KIIα to autophagosomes regulates PtdIns4P-dependent autophagosome-lysosome fusion

For decades, phosphatidylinositol 4-phosphate (PtdIns4P) was considered primarily as a precursor in the synthesis of phosphatidylinositol(4,5)bisphosphate (PtdIns(4,5)P(2)). More recently, specific functions for PtdIns4P itself have been identified, particularly in the regulation of intracellular me...

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Vydáno v:Autophagy
Hlavní autoři: Albanesi, Joseph, Wang, Hanzhi, Sun, Hui-Qiao, Levine, Beth, Yin, Helen
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Autophagic Punctum
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824573/
https://ncbi.nlm.nih.gov/pubmed/26391226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1093718
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