Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23

AIMS: To investigate the effects and underlying mechanism of dexmedetomidine on the cultured human dendritic cells (DCs). METHODS: Human DCs and cytotoxic T lymphocytes (CTLs) were obtained from human cord blood mononuclear cells by density gradient centrifugation. Cultured DCs were divided into thr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Gong, Le, Yuan, Zhou, Lei, Gong, Li, Li, Xiaoxiao, Li, Yunli, Liao, Qin, Duan, Kaiming, Tong, Jianbin, Ouyang, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824534/
https://ncbi.nlm.nih.gov/pubmed/27054340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153288
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