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Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase

Antigen-presenting cells expressing indoleamine 2,3-dioxygenase (IDO) play a critical role in maintaining peripheral tolerance. Strategies to inhibit IDO gene expression and enhance antigen-presenting cell function might improve anti-tumour immunity. Here we have designed highly effective anti-IDO s...

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Bibliografiska uppgifter
Huvudupphovsmän: Flatekval, Gro F, Sioud, Mouldy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753901/
https://ncbi.nlm.nih.gov/pubmed/19740345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03093.x
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