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Clearing Persistent Extracellular Antigen of Hepatitis B Virus: An Immunomodulatory Strategy to Reverse Tolerance for an Effective Therapeutic Vaccination

Development of therapeutic vaccines/strategies to control chronic hepatitis B virus (HBV) infection (CHB) has been challenging due to HBV-induced tolerance. In this study, we explored strategies for breaking tolerance and restoring the immune response to the HBV surface antigen in tolerant mice. We...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Zhu, Danming, Liu, Longchao, Yang, Dan, Fu, Sherry, Bian, Yingjie, Sun, Zhichen, He, Junming, Su, Lishan, Zhang, Liguo, Peng, Hua, Fu, Yang-Xin
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824405/
https://ncbi.nlm.nih.gov/pubmed/26936879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502061
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