LIGHT Induces Distinct Signals to Clear an AAV-Expressed Persistent Antigen in the Mouse Liver and to Induce Liver Inflammation

BACKGROUND: Infection with adeno-associated virus (AAV) vector with liver tropism leads to persistent expression of foreign antigens in the mouse liver, with no significant liver inflammation or pathology. This provides a model to investigate antigen persistence in the liver and strategies to modula...

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Bibliografiska uppgifter
Huvudupphovsmän: Washburn, Michael L., Kovalev, Grigoriy I., Koroleva, Ekaterina, Fu, Yang-Xin, Su, Lishan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871052/
https://ncbi.nlm.nih.gov/pubmed/20498840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010585
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