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A new MCM modification cycle regulates DNA replication initiation
The MCM DNA helicase is a central regulatory target during genome replication. MCM is kept inactive during G1 and activated in S phase to initiate replication. During this transition, the only known chemical change on MCM is the gain of multi-site phosphorylation that promotes cofactor recruitment....
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823995/ https://ncbi.nlm.nih.gov/pubmed/26854664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3173 |
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