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Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway

Dihydroartemisinin (DHA) is a widely used antimalarial drug isolated from the plant Artemisia annua. Recent studies suggested that DHA has antitumor effects utilizing its reactive oxygen species (ROS) yielding mechanism. Here, we reported that DHA is inhibitory on lipopolysaccharide (LPS)-induced os...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Dou, C, Ding, N, Xing, J, Zhao, C, Kang, F, Hou, T, Quan, H, Chen, Y, Dai, Q, Luo, F, Xu, J, Dong, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823966/
https://ncbi.nlm.nih.gov/pubmed/27031959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.69
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