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Simvastatin Inhibits Lipopolysaccharide-Induced Osteoclastogenesis and Reduces Alveolar Bone Loss in Experimental Periodontal Disease
BACKGROUND AND OBJECTIVE: Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and have anti-inflammatory effects independent of cholesterol lowering. Recent clinical studies have indicated that statin intake has beneficial effect on periodontal disease. However, the underlying...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979522/ https://ncbi.nlm.nih.gov/pubmed/24117880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jre.12132 |
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